Leucodermia and Premature Canities

Serum Iron, Ferritin and Calcium Levels in Premature Canities

Background: Premature canities is defined as a minimum of five gray hairs present in a person less than 20 years of age. Etiologically, it is genetically mediated or may be associated with autoimmune syndromes. Few studies have found an association of decreased levels of trace elements with early canities, however the scientific evidence for the same is lacking. Aims and objectives: of this stu...

Prospective Analytical Controlled Study Evaluating Serum Biotin, Vitamin B12, and Folic Acid in Patients with Premature Canities

BACKGROUND Premature canities is a common yet unfathomed disorder. The evidence for the role of micronutrient deficiency in premature canities is not well established. AIM The present study was undertaken to evaluate the micronutrient levels in Indian patients with premature canities as compared to controls. MATERIALS AND METHODS We conducted a case-control study in 52 self-reporting patien...

Micafungin in Premature and Non-premature Infants

BACKGROUND Invasive fungal infections cause excessive morbidity and mortality in premature neonates and severely ill infants. METHODS Safety and efficacy outcomes of micafungin were compared between prematurely and non-prematurely born infants <2 years of age. Data were obtained from all completed phase I-III clinical trials with micafungin that had enrolled infants (<2 years of age) that wer...

Normal and Premature Adrenarche

Premature complexes and pauses

A 42 yr old woman from Zambia presented with complaints of fatigue and occasional palpitations for four months. The palpitations were momentary and recurrent but never sustained. She had a history of hypertensionwhich was well controlled on telmisartan. Other than that, the past history was unremarkable. Below is the ECG at presentation. Recurrent premature complexes and pauses are seen. How ar...